紀錄類型 ： 書目-語言資料,印刷品: 單行本

出版者 ： [S.l.] :SPRINGER VERLAG, SINGAPOR,2023.

面頁冊數 ： 1 online resource

內容註 ： Intro -- Preface -- Acknowledgements -- Contents -- Editors and Contributors -- 1: Regeneration and Tissue Microenvironment -- 1.1 Introduction -- 1.2 Role of Tissue Microenvironment -- 1.2.1 Cells -- 1.2.1.1 Stem Cells -- 1.2.1.2 Fibroblasts -- 1.2.1.3 Immune Cells -- 1.2.1.4 Platelets -- 1.2.2 Extracellular Matrix -- 1.2.2.1 Collagen -- 1.2.2.2 Fibronectin -- 1.2.2.3 Glycosaminoglycans (GAGs) -- 1.2.2.4 Proteoglycans -- 1.2.3 Soluble Signaling Molecules -- 1.3 Regeneration -- 1.4 Conclusion -- References -- 2: Non-stem Cell Mediated Tissue Regeneration and Repair -- 2.1 Introduction -- 2.1.1 Regeneration and Repair: Are They the Same? -- 2.1.2 Stem Cells and Tissue Repair -- 2.1.3 Stem Cells vs. Non-stem Cells -- 2.1.3.1 Stem Cells -- 2.1.3.2 Non-stem Cells -- 2.1.4 Regenerative Medicine Beyond the Stem Cells -- 2.2 Types of Non-stem Cell Mediated Regeneration and Repair -- 2.2.1 Naturally Occurring -- 2.2.1.1 Olfactory Ensheathing Cells (OECs) -- 2.2.1.2 Schwann Cells -- 2.2.1.3 Epithelial Basal Cells -- 2.2.1.4 Endothelial Progenitor Cells -- 2.2.1.5 Precursor or ``-Blast´´ Cells -- 2.2.1.6 Satellite Cells -- 2.2.2 Clinically Available -- 2.2.2.1 Cellular Approaches -- 2.2.2.2 Acellular Approaches -- 2.2.3 Under Exploration -- 2.2.3.1 Cellular Approaches -- Nullipotent Cells -- Blast or Precursor Cells -- 2.2.3.2 Acellular Approaches -- 2.2.3.3 Combination Based -- 2.3 Conclusion -- References -- 3: Immunological Perspectives Involved in Tissue Engineering -- 3.1 Introduction -- 3.2 Biomaterials and Tissue Engineering -- 3.2.1 Metallic Biomaterials -- 3.2.2 Ceramic Biomaterials -- 3.2.3 Polymer Biomaterials -- 3.3 Immunological Response to Biomaterials Used in Tissue Engineering -- 3.3.1 Innate Immune Response to Biomaterials -- 3.3.2 Adaptive Immune Response to Biomaterials.

內容註 ： 3.4 Need for Graft and Their Interaction with the Recipient´s Immune System -- 3.5 Modulation of the Host Immune Response by Biomaterials -- 3.5.1 Immune Pathways Modulated by Foreign Molecules and Biomaterials -- 3.5.2 Macrophage Polarization-Mediated Immune Modulation -- 3.5.3 Immune Responses to Nanomaterials in Tissue Engineering -- 3.5.4 Immunomodulation by Stem Cells Used in Engineered Tissue -- 3.6 Future Perspectives and Conclusion -- References -- 4: Advances in Medical Imaging for Wound Repair and Regenerative Medicine -- 4.1 Need for Imaging -- 4.2 The Process of Skin Wound Healing -- 4.3 Scar Fibrosis -- 4.4 Imaging in Wound Healing -- 4.4.1 Surface Imaging (Digital Photography) -- 4.4.2 Optical Coherence Tomography -- 4.4.3 Laser Doppler Imaging (LDI) -- 4.4.4 Laser Speckle Imaging (LSI) -- 4.4.5 Fluorescence Imaging -- 4.4.6 Spectral Imaging -- 4.4.7 Ultrasonography -- 4.4.8 Photoacoustic Imaging (PAI) -- 4.4.9 Thermal Imaging -- 4.5 Prospects for Advancements in Current Systems for Assessment of Healing -- 4.5.1 Imaging for Biochemical Analysis of Wounds by Micro-spectroscopy -- 4.5.2 Monitoring Drug Delivery for Identifying Therapeutic Efficacy -- References -- 5: Role of Biosensors in Regenerative Therapeutics: Past, Present, and Future Prospects -- 5.1 Introduction -- 5.2 Envisaging Direction in Regenerative Medicine -- 5.3 Recent Perspective into the Role of Stromal Cell in Regenerative Medicine -- 5.4 General Biosensing Technologies -- 5.5 Biomarkers in Regenerative Medicine -- 5.6 Conventional Strategies for Sensing of Biomolecules -- 5.7 Biosensors in Regenerative Medicine -- 5.7.1 Biosensors to Detect Pluripotent Stromal Cells -- 5.7.2 Biosensor Prospect in Cartilage Regeneration -- 5.7.3 Biosensor for Prolotherapy -- 5.7.4 Regenerative Medicine On Chip -- 5.8 Nanotechnology in Regenerative Medicine.

內容註 ： 5.9 Bioprocess Control and Therapeutic Applications in Regenerative Medicine -- 5.10 Conclusions -- References -- 6: Acute and Chronic Wound Management: Assessment, Therapy and Monitoring Strategies -- 6.1 Introduction -- 6.2 Physiology of Wound Healing -- 6.2.1 Factors Affecting Wound Healing -- 6.3 Challenges Faced in the Wound Healing Procedure -- 6.4 Therapeutic Strategies -- 6.4.1 Traditional Methods -- 6.4.1.1 Debridement and Dressing -- 6.4.1.2 Skin Grafts -- 6.4.1.3 Hyperbaric Oxygen Therapy -- 6.4.1.4 Negative Pressure Wound Therapy (NPWT) -- 6.4.2 Advanced and Emerging Methods -- 6.4.2.1 Tissue Engineered Grafting -- 6.4.2.2 Genetic Editing (miRNA) -- 6.4.2.3 Phototreatment -- 6.4.2.4 Magnetic Therapy -- 6.4.2.5 Microwave Therapy -- 6.4.2.6 Nanotechnology for Wound Therapy -- 6.5 Assessment and Monitoring Wound Healing -- 6.5.1 Invasive Assessment Techniques -- 6.5.2 Non-invasive Assessment Techniques -- 6.5.2.1 OCT Imaging -- 6.5.2.2 High-Frequency Ultrasound Imaging -- 6.5.3 Wound Healing Models and Quantitative Analysis of the Wounds -- 6.6 Conclusion -- References -- 7: Stem Cells and Therapies in Cardiac Regeneration -- 7.1 Cardiac Regeneration -- 7.1.1 Cardiomyocyte Loss During Myocardial Infarction -- 7.1.2 Cell Cycle and Cardiomyocyte Proliferation -- 7.1.3 Stem Cells as a Model for Cardiac Regeneration -- 7.1.3.1 Multipotent Stem Cells -- Fetal Stem Cells -- Adult Stem Cells -- Cardiac Stem Cells -- 7.1.3.2 Pluripotent Stem Cells -- Embryonic Stem Cells -- Induced Pluripotent Stem Cells -- 7.2 Noncoding RNAs and Cardiac Regeneration -- References -- 8: Hydrogel-Based Tissue-Mimics for Vascular Regeneration and Tumor Angiogenesis -- 8.1 Introduction -- 8.2 Microenvironmental Considerations for Vascular Regeneration -- 8.3 Microenvironmental Considerations for Tumor Angiogenesis.

內容註 ： 8.4 Hydrogel-Based Models for Vascular Regeneration and Tumor Angiogenesis -- 8.4.1 Matrigel -- 8.4.2 Collagen and Gelatin -- 8.4.3 Fibrin -- 8.4.4 Alginate and Agarose -- 8.4.5 Other Natural Materials -- 8.4.6 Poly(ethylene Glycol) -- 8.4.7 Poly(lactic-co-Glycolic Acid) and Poly(caprolactone) -- 8.4.8 Hybrid Hydrogels -- 8.5 Biofabrication Strategies for Vasculogenesis and Angiogenesis -- 8.5.1 Self-Assembly -- 8.5.2 Bioprinting -- 8.5.3 Electrospinning -- 8.5.4 Micromolding -- 8.5.5 Photolithography and Laser-Based Techniques -- 8.6 Conclusions -- References -- 9: Advances in 3D Printing Technology for Tissue Engineering -- 9.1 Introduction -- 9.2 Printing Technology -- 9.2.1 Laser-Assisted -- 9.2.2 Laser-Induced Printing -- 9.2.3 Laser-Guided Printing -- 9.2.4 Stereolithography Apparatus (SLA) -- 9.2.5 Digital Light Projection (DLP) -- 9.2.6 Two-Photon Polymerization (TPP) -- 9.2.7 Extrusion-Based Printing System -- 9.2.8 Inkjet Printing System -- 9.3 Types of Biomaterial Inks Used in 3D Printing -- 9.3.1 Polymer-Based Inks -- 9.3.2 Ceramic-Based Inks -- 9.3.3 Composite Inks -- 9.4 Application of 3D Printing in Tissue Engineering -- 9.4.1 Nervous Tissue -- 9.4.2 Liver -- 9.4.3 Kidney -- 9.4.4 Skin -- 9.4.5 Bone and Cartilage -- 9.4.6 Ocular Tissues -- 9.4.7 Ears -- 9.5 Conclusion -- References -- 10: Adult Neurogenesis: A Potential Target for Regenerative Medicine -- 10.1 History of Adult Neurogenesis -- 10.2 Factors Influencing Adult Neurogenesis -- 10.3 Anatomical and Physiological Properties of Adult Formed Neurons -- 10.3.1 Distinct Timeline of Evolution of Morphological Features in Adult Formed Neurons -- Box 10.1 Species Specific Differences of Adult Formed Neurons -- 10.3.2 Physiological Features of Adult Formed Neurons -- 10.4 Functional Roles of Adult Neurogenesis -- 10.4.1 Learning and Memory.

內容註 ： 10.4.2 Pattern Separation and Pattern Completion -- 10.4.3 Higher Order Cognitive Functionalities -- 10.5 Adult Neurogenesis: A Target for Regenerative Medicine -- 10.5.1 Stroke and Injuries -- 10.5.2 Neurodegenerative Conditions -- 10.5.3 Neuropsychiatric Conditions -- 10.5.4 Potential Roles in Learning and Cognitive Functionalities -- Box 10.2 Outstanding Questions and Future Directions -- References -- 11: Regenerative Approaches in the Nervous System -- 11.1 Background -- 11.1.1 Anatomy and Organisation of the Nervous System -- 11.1.2 Function of the Nervous System -- 11.1.3 Barriers Protecting the CNS -- 11.1.4 Pathophysiology of Nervous System Injuries -- 11.2 Issues with Natural Regeneration and Repair -- 11.2.1 CNIs -- 11.2.2 PNI -- 11.2.3 Potential Strategies for Regeneration and Repair -- 11.3 Current Approaches for Clinical Management -- 11.3.1 Brain Injury -- 11.3.1.1 Diagnostics -- 11.3.2 Spinal Cord Injury -- 11.3.2.1 Diagnostics -- 11.3.2.2 Management -- 11.3.3 Peripheral Nerve Injury -- 11.3.3.1 Diagnostics -- 11.3.3.2 Management -- 11.4 Novel Regenerative Approaches -- 11.4.1 Brain Injury -- 11.4.1.1 Cell Transplantation-Based Approaches -- 11.4.1.2 Biomaterial-Based Approaches -- 11.4.1.3 Bioactive Molecule-Based Approaches -- 11.4.2 Spinal Cord Injury -- 11.4.2.1 Cell Transplantation-Based Approaches -- 11.4.2.2 Biomaterial-Based Approaches -- 11.4.2.3 Bioactive Molecule-Based Approaches -- 11.4.2.4 Combination-Based Approaches -- 11.4.3 Peripheral Nerve Injury -- 11.4.3.1 Cell-Based Approaches -- 11.4.3.2 Biomaterial-Based Approaches -- 11.4.3.3 Bioactive Molecule-Based Approaches -- 11.4.3.4 Combination-Based and Other Approaches -- 11.5 Translational Needs -- References -- 12: Prenatal Interventions for the Treatment of Congenital Disorders -- 12.1 Introduction -- 12.2 Technological Advances in Early Diagnosis.

標題 ： Regenerative medicine. -

標題 ： Stem cells. -

標題 ： Nervous system--Regeneration. -

標題 ： Biomaterials. -

標題 ： Cells. -

標題 ： Regenerative Medicine -

標題 ： Stem Cells -

標題 ： Cells -

ISBN ： 9789811960086

ISBN ： 9811960089

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