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Model-assisted Bayesian designs for dose finding and optimization :methods and applications /
紀錄類型 ： 書目-語言資料,印刷品: 單行本
作者 ： Yuan, Ying
其他作者 ： Lin, Ruitao,
出版項 ： Boca Raton :Chapman & Hall/CRC,2022.
面頁冊數 ： 1 online resource.
附註 ： <B><P>1. Bayesian Statistics and Adaptive Designs</B>. 1.1. Basics of Bayesian Statistics. 1.2. Bayesian Adaptive Designs. 1.2. Bayesian Adaptive Designs. <B>2. Algorithm and Model-Based Dose Finding Designs</B>. 2.1 Introduction. 2.2. Traditional 3+3 Design. 2.3. Cohort Expansion. 2.4 Accelerated Titration Design. 2.5. Continual Reassessment Method. 2.6. Bayesian Model Averaging CRM. 2.7. Escalation with Overdose Control. 2.8. Bayesian Logistic Regression Method. 2.9. Software. <STRONG>3. Model-Assisted Dose Finding Designs.</STRONG> 3.1. Introduction. 3.2. Modified Toxicity Probability Interval Design. 3.3. Keyboard Design. 3.4. 3.4 Bayesian Optimal Interval (BOIN) Design. 3.5. Operating Characteristics. 3.6. Software and Case Study. <STRONG>4. Drug-Combination Trials.</STRONG> 4.1. Introduction. 4.2. Model-based Designs. 4.3. Model-assisted Designs. 4.4. Operating Characteristics. 4.5. Software and Case Study. <STRONG>5. Late-Onset Toxicity.</STRONG> 5.1. A Common Logistical Problem. 5.2. Late-Onset Toxicities. 5.3. TITE-CRM. 5.4. TITE-BOIN. 5.5. A Unified Approach using "Effective" Data. 5.6. TITE-keyboard and TITE-mTPI designs. 5.7. Software and Case Study. <STRONG>6. Incorporating Historical Data. </STRONG>6.1. Historical Data and Prior Information. 6.2. Informative BOIN (iBOIN). 6.3. iKeyboard Design. 6.4. Operating Characteristics. 6.5. Software and Case Study. <STRONG>7. Multiple Toxicity Grades.</STRONG> 7.1. Multiple Toxicity Grades. 7.2. gBOIN Accounting for Toxicity Grade. 7.3. Multiple-toxicity BOIN. 7.4. Software and Illustration. <STRONG>8. Finding Optimal Biological Dose.</STRONG> 8.1. Introduction. 8.2. EffTox design. 8.3. U-BOIN Design. 8.4. BOIN12 Design. 8.5. TITE-BOIN12 Design. 8.6. Other Model-Assisted Phase I/II Designs. 8.7. Software and Case Study. Bibliography. Index. </P>
標題 ： Drug development - Statistical methods. -
版本 ： 1st.
ISBN ： 9780429626838
ISBN ： 0429626835
ISBN ： 9780429628474
ISBN ： 0429628471
ISBN ： 9780429052781
ISBN ： 0429052782
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250 $a1st.
264 1$aBoca Raton :$bChapman & Hall/CRC,$c2022.
300 $a1 online resource.
336 $atext$2rdacontent
337 $acomputer$2rdamedia
338 $aonline resource$2rdacarrier
490 0 $aChapman & Hall/CRC biostatistics series
500 $a<B><P>1. Bayesian Statistics and Adaptive Designs</B>. 1.1. Basics of Bayesian Statistics. 1.2. Bayesian Adaptive Designs. 1.2. Bayesian Adaptive Designs. <B>2. Algorithm and Model-Based Dose Finding Designs</B>. 2.1 Introduction. 2.2. Traditional 3+3 Design. 2.3. Cohort Expansion. 2.4 Accelerated Titration Design. 2.5. Continual Reassessment Method. 2.6. Bayesian Model Averaging CRM. 2.7. Escalation with Overdose Control. 2.8. Bayesian Logistic Regression Method. 2.9. Software. <STRONG>3. Model-Assisted Dose Finding Designs.</STRONG> 3.1. Introduction. 3.2. Modified Toxicity Probability Interval Design. 3.3. Keyboard Design. 3.4. 3.4 Bayesian Optimal Interval (BOIN) Design. 3.5. Operating Characteristics. 3.6. Software and Case Study. <STRONG>4. Drug-Combination Trials.</STRONG> 4.1. Introduction. 4.2. Model-based Designs. 4.3. Model-assisted Designs. 4.4. Operating Characteristics. 4.5. Software and Case Study. <STRONG>5. Late-Onset Toxicity.</STRONG> 5.1. A Common Logistical Problem. 5.2. Late-Onset Toxicities. 5.3. TITE-CRM. 5.4. TITE-BOIN. 5.5. A Unified Approach using "Effective" Data. 5.6. TITE-keyboard and TITE-mTPI designs. 5.7. Software and Case Study. <STRONG>6. Incorporating Historical Data. </STRONG>6.1. Historical Data and Prior Information. 6.2. Informative BOIN (iBOIN). 6.3. iKeyboard Design. 6.4. Operating Characteristics. 6.5. Software and Case Study. <STRONG>7. Multiple Toxicity Grades.</STRONG> 7.1. Multiple Toxicity Grades. 7.2. gBOIN Accounting for Toxicity Grade. 7.3. Multiple-toxicity BOIN. 7.4. Software and Illustration. <STRONG>8. Finding Optimal Biological Dose.</STRONG> 8.1. Introduction. 8.2. EffTox design. 8.3. U-BOIN Design. 8.4. BOIN12 Design. 8.5. TITE-BOIN12 Design. 8.6. Other Model-Assisted Phase I/II Designs. 8.7. Software and Case Study. Bibliography. Index. </P>
504 $aIncludes bibliographical references and index.
533 $aElectronic reproduction.$bIpswich, MA$nAvailable via World Wide Web.
588 $aDescription based on CIP data; resource not viewed.
650 0$aDrug development$xStatistical methods.$335926
700 1 $aLin, Ruitao,$eauthor.$3100593
700 1 $aLee, J. Jack,$eauthor.$3100594
710 2 $aEBSCOhost$387894
776 08$iPrint version :$z9780367146245
856 40$uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=3411158$zClick to View (限總院院內)
Yuan, Ying(Professor of biostatistics),
Model-assisted Bayesian designs for dose finding and optimization :methods and applications /Ying Yuan, Ruitao Lin, J. Jack Lee. - 1st. - 1 online resource. - Chapman & Hall/CRC biostatistics series.
Includes bibliographical references and index.
Electronic reproduction.
Ipswich, MA
Available via World Wide Web.
ISBN: 9780429626838
Standard No.: 10.1201/9780429052781doi
Source: 9780429626838Ingram Content GroupSubjects--Topical Terms:
35926
Drug development
--Statistical methods.
LC Class. No.: RM301.25
Dewey Class. No.: 615.19
Model-assisted Bayesian designs for dose finding and optimization :methods and applications /Ying Yuan, Ruitao Lin, J. Jack Lee. - 1st. - 1 online resource. - Chapman & Hall/CRC biostatistics series.
1. Bayesian Statistics and Adaptive Designs. 1.1. Basics of Bayesian Statistics. 1.2. Bayesian Adaptive Designs. 1.2. Bayesian Adaptive Designs. 2. Algorithm and Model-Based Dose Finding Designs. 2.1 Introduction. 2.2. Traditional 3+3 Design. 2.3. Cohort Expansion. 2.4 Accelerated Titration Design. 2.5. Continual Reassessment Method. 2.6. Bayesian Model Averaging CRM. 2.7. Escalation with Overdose Control. 2.8. Bayesian Logistic Regression Method. 2.9. Software. 3. Model-Assisted Dose Finding Designs. 3.1. Introduction. 3.2. Modified Toxicity Probability Interval Design. 3.3. Keyboard Design. 3.4. 3.4 Bayesian Optimal Interval (BOIN) Design. 3.5. Operating Characteristics. 3.6. Software and Case Study. 4. Drug-Combination Trials. 4.1. Introduction. 4.2. Model-based Designs. 4.3. Model-assisted Designs. 4.4. Operating Characteristics. 4.5. Software and Case Study. 5. Late-Onset Toxicity. 5.1. A Common Logistical Problem. 5.2. Late-Onset Toxicities. 5.3. TITE-CRM. 5.4. TITE-BOIN. 5.5. A Unified Approach using "Effective" Data. 5.6. TITE-keyboard and TITE-mTPI designs. 5.7. Software and Case Study. 6. Incorporating Historical Data. 6.1. Historical Data and Prior Information. 6.2. Informative BOIN (iBOIN). 6.3. iKeyboard Design. 6.4. Operating Characteristics. 6.5. Software and Case Study. 7. Multiple Toxicity Grades. 7.1. Multiple Toxicity Grades. 7.2. gBOIN Accounting for Toxicity Grade. 7.3. Multiple-toxicity BOIN. 7.4. Software and Illustration. 8. Finding Optimal Biological Dose. 8.1. Introduction. 8.2. EffTox design. 8.3. U-BOIN Design. 8.4. BOIN12 Design. 8.5. TITE-BOIN12 Design. 8.6. Other Model-Assisted Phase I/II Designs. 8.7. Software and Case Study. Bibliography. Index.
Includes bibliographical references and index.
Electronic reproduction.
Ipswich, MA
Available via World Wide Web.
ISBN: 9780429626838
Standard No.: 10.1201/9780429052781doi
Source: 9780429626838Ingram Content GroupSubjects--Topical Terms:
35926
Drug development
--Statistical methods.
LC Class. No.: RM301.25
Dewey Class. No.: 615.19
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