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Drug repurposing for emerging infectious diseases and cancer /
紀錄類型 ： 書目-語言資料,印刷品: 單行本
其他作者 ： Sobti, R. C.
出版項 ： Singapore :Springer,2023.
面頁冊數 ： 1 online resource
內容註 ： Intro -- Preface -- Contents -- Editors and Contributors -- Chapter 1: Drug Repurposing: An Advance Way to Traditional Drug Discovery -- 1.1 Introduction -- 1.2 Rationale of Drug Repurposing -- 1.3 Role of Drug Repurposing in Conventional Pharmaceutical Market -- 1.4 Roadmap to Modern Drug Repurposing -- 1.5 Drug Repurposing Strategies and Approaches -- 1.5.1 Computational Approaches -- 1.5.2 Experimental Approaches -- 1.6 Opportunity and Challenges in Drug Repurposing -- 1.7 Conclusion -- References -- Chapter 2: Drug Polypharmacology Toward Drug Repurposing -- 2.1 Drug Pharmacology
內容註 ： 2.2 Drug Repurposing -- 2.3 Need for Drug Repurposing -- 2.4 Challenges of Drug Repurposing -- 2.5 Different Strategies of Drug Repurposing -- 2.6 Methodology for Drug Repurposing -- 2.6.1 Virtual Screening -- 2.6.2 Structure Prediction of Target -- 2.7 Chemical Composition of Drug -- 2.8 Prediction of Protein Binding Site -- 2.9 Successful Example of Drug Repurposing -- References -- Chapter 3: Pharmacovigilance-Based Drug Repurposing -- 3.1 Drug Development and Pharmacovigilance -- 3.1.1 Need for Pharmacovigilance -- 3.2 Pharmacovigilance and Drug Repurposing -- 3.2.1 Serendipity
內容註 ： 3.2.2 Signature Matching -- 3.2.3 Mechanistic Profiling -- 3.2.4 Inverse Signals -- 3.2.4.1 Signal -- 3.2.4.1.1 Inverse Signal -- 3.3 The Process of Drug Repurposing -- 3.3.1 Present Scenario -- 3.3.1.1 Alzheimer�s Disease -- 3.3.1.2 Raynaud�s Phenomenon (RP) -- 3.3.1.3 COVID-19 -- 3.4 Future Perspectives -- Further Reading -- Chapter 4: In Silico Analysis of Cellular Interactors of PQBP1 for Potential Drug Repurposing -- 4.1 Introduction -- 4.2 Material and Methods -- 4.3 Results and Discussion -- References -- Chapter 5: Drug Repurposing Opportunities in Cancer -- 5.1 Introduction
內容註 ： 5.2 Drug Repurposing -- 5.3 Drug Repurposing Barriers -- 5.4 Computational Approaches in Drug Repurposing -- 5.5 Drug Repurposing in Cancer -- 5.5.1 Importance of Drug Repurposing in Cancer Treatment -- 5.5.2 Repurposing Small-Molecule Non-Oncology Drugs -- 5.5.2.1 Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) -- 5.5.2.1.1 Aspirin -- 5.5.2.1.2 Diclofenac -- 5.5.2.1.3 Ibuprofen -- 5.5.2.1.4 Naproxen -- 5.5.2.2 Statins -- 5.5.2.2.1 Simvastatin -- 5.5.2.3 Antidiabetic Drugs -- 5.5.2.3.1 Metformin -- 5.5.2.3.2 Phenformin -- 5.5.2.4 Selective Estrogen Receptor Modulators (SERMs)
內容註 ： 5.5.2.4.1 Raloxifene -- 5.5.2.5 Antidepressants -- 5.5.2.5.1 Imipramine -- 5.5.2.5.2 Trifluoperazine -- 5.5.2.5.3 Fluoxetine -- 5.5.2.6 Antipsychotic -- 5.5.2.6.1 Chlorpromazine -- 5.5.2.7 Anticonvulsant -- 5.5.2.7.1 Valproic Acid -- 5.5.2.8 Antiviral Drugs -- 5.5.2.8.1 Ritonavir -- 5.5.2.8.2 Nelfinavir -- 5.5.2.8.3 Lopinavir -- 5.5.2.9 Antibiotics -- 5.5.2.9.1 Ciprofloxacin -- 5.5.2.9.2 Nifuroxazide -- 5.5.2.9.3 Moxifloxacin -- 5.5.2.10 Antifungals -- 5.5.2.10.1 Clotrimazole -- 5.5.2.10.2 Itraconazole -- 5.5.2.11 Antiepileptic Drug -- 5.5.2.11.1 Flunarizine -- 5.5.2.11.2 Prazosin
標題 ： Drug development. -
標題 ： Communicable diseases - Chemotherapy. -
ISBN ： 9789811953996
ISBN ： 9811953996
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505 0 $aIntro -- Preface -- Contents -- Editors and Contributors -- Chapter 1: Drug Repurposing: An Advance Way to Traditional Drug Discovery -- 1.1 Introduction -- 1.2 Rationale of Drug Repurposing -- 1.3 Role of Drug Repurposing in Conventional Pharmaceutical Market -- 1.4 Roadmap to Modern Drug Repurposing -- 1.5 Drug Repurposing Strategies and Approaches -- 1.5.1 Computational Approaches -- 1.5.2 Experimental Approaches -- 1.6 Opportunity and Challenges in Drug Repurposing -- 1.7 Conclusion -- References -- Chapter 2: Drug Polypharmacology Toward Drug Repurposing -- 2.1 Drug Pharmacology
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505 8 $a3.2.2 Signature Matching -- 3.2.3 Mechanistic Profiling -- 3.2.4 Inverse Signals -- 3.2.4.1 Signal -- 3.2.4.1.1 Inverse Signal -- 3.3 The Process of Drug Repurposing -- 3.3.1 Present Scenario -- 3.3.1.1 Alzheimer�s Disease -- 3.3.1.2 Raynaud�s Phenomenon (RP) -- 3.3.1.3 COVID-19 -- 3.4 Future Perspectives -- Further Reading -- Chapter 4: In Silico Analysis of Cellular Interactors of PQBP1 for Potential Drug Repurposing -- 4.1 Introduction -- 4.2 Material and Methods -- 4.3 Results and Discussion -- References -- Chapter 5: Drug Repurposing Opportunities in Cancer -- 5.1 Introduction
505 8 $a5.2 Drug Repurposing -- 5.3 Drug Repurposing Barriers -- 5.4 Computational Approaches in Drug Repurposing -- 5.5 Drug Repurposing in Cancer -- 5.5.1 Importance of Drug Repurposing in Cancer Treatment -- 5.5.2 Repurposing Small-Molecule Non-Oncology Drugs -- 5.5.2.1 Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) -- 5.5.2.1.1 Aspirin -- 5.5.2.1.2 Diclofenac -- 5.5.2.1.3 Ibuprofen -- 5.5.2.1.4 Naproxen -- 5.5.2.2 Statins -- 5.5.2.2.1 Simvastatin -- 5.5.2.3 Antidiabetic Drugs -- 5.5.2.3.1 Metformin -- 5.5.2.3.2 Phenformin -- 5.5.2.4 Selective Estrogen Receptor Modulators (SERMs)
505 8 $a5.5.2.4.1 Raloxifene -- 5.5.2.5 Antidepressants -- 5.5.2.5.1 Imipramine -- 5.5.2.5.2 Trifluoperazine -- 5.5.2.5.3 Fluoxetine -- 5.5.2.6 Antipsychotic -- 5.5.2.6.1 Chlorpromazine -- 5.5.2.7 Anticonvulsant -- 5.5.2.7.1 Valproic Acid -- 5.5.2.8 Antiviral Drugs -- 5.5.2.8.1 Ritonavir -- 5.5.2.8.2 Nelfinavir -- 5.5.2.8.3 Lopinavir -- 5.5.2.9 Antibiotics -- 5.5.2.9.1 Ciprofloxacin -- 5.5.2.9.2 Nifuroxazide -- 5.5.2.9.3 Moxifloxacin -- 5.5.2.10 Antifungals -- 5.5.2.10.1 Clotrimazole -- 5.5.2.10.2 Itraconazole -- 5.5.2.11 Antiepileptic Drug -- 5.5.2.11.1 Flunarizine -- 5.5.2.11.2 Prazosin
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Drug repurposing for emerging infectious diseases and cancer /Ranbir Chander Sobti, Sunil K. Lal, Ramesh K. Goyal, editors. - 1 online resource
Intro -- Preface -- Contents -- Editors and Contributors -- Chapter 1: Drug Repurposing: An Advance Way to Traditional Drug Discovery -- 1.1 Introduction -- 1.2 Rationale of Drug Repurposing -- 1.3 Role of Drug Repurposing in Conventional Pharmaceutical Market -- 1.4 Roadmap to Modern Drug Repurposing -- 1.5 Drug Repurposing Strategies and Approaches -- 1.5.1 Computational Approaches -- 1.5.2 Experimental Approaches -- 1.6 Opportunity and Challenges in Drug Repurposing -- 1.7 Conclusion -- References -- Chapter 2: Drug Polypharmacology Toward Drug Repurposing -- 2.1 Drug Pharmacology
Electronic reproduction.
Ipswich, MA
Available via World Wide Web.
ISBN: 9789811953996
Standard No.: 10.1007/978-981-19-5399-6doiSubjects--Topical Terms:
80152
Drug development.
LC Class. No.: RM301.25 / .D78 2023
Dewey Class. No.: 615.1/9
Intro -- Preface -- Contents -- Editors and Contributors -- Chapter 1: Drug Repurposing: An Advance Way to Traditional Drug Discovery -- 1.1 Introduction -- 1.2 Rationale of Drug Repurposing -- 1.3 Role of Drug Repurposing in Conventional Pharmaceutical Market -- 1.4 Roadmap to Modern Drug Repurposing -- 1.5 Drug Repurposing Strategies and Approaches -- 1.5.1 Computational Approaches -- 1.5.2 Experimental Approaches -- 1.6 Opportunity and Challenges in Drug Repurposing -- 1.7 Conclusion -- References -- Chapter 2: Drug Polypharmacology Toward Drug Repurposing -- 2.1 Drug Pharmacology
Electronic reproduction.
Ipswich, MA
Available via World Wide Web.
ISBN: 9789811953996
Standard No.: 10.1007/978-981-19-5399-6doiSubjects--Topical Terms:
80152
Drug development.
LC Class. No.: RM301.25 / .D78 2023
Dewey Class. No.: 615.1/9
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