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Handbook of statistics in clinical oncology /
紀錄類型 ： 書目-語言資料,印刷品: 單行本
其他作者 ： Crowley, John,
出版者 ： Boca Raton :2006.Chapman & Hall/CRC,
面頁冊數 ： 617 p. :ill. ;25 cm.
內容註 ： Overview of phase I trials -- Phase I and phase I/II dose finding algorithms using continual reassessment method -- Choosing a phase I design -- Pharmacokinetics in clinical oncology: statistical issues -- Practical implementation of the continual reassessment method -- Overview of Phase II clinical trials -- Designs based on toxicity and response -- Phase II trials using time-to-event endpoints -- Phase II selection designs -- On use of covariates in randomization and analysis of clinical trials -- Factorial designs with time to event endpoints -- Noninferiority trials -- Power and sample size for phase III clinical trials of survival -- Early stopping of cancer clinical trials -- Design and analysis of quality of life data -- Economic analyses alongside cancer clinical trials -- Prognostic factor studies -- Statistical methods to identify predictive factors -- Explained variation in proportional hazards regression -- Constructing prognostic groups by tree-based partitioning and peeling methods -- Clinical monitoring based on joint models for longitudinal biomarkers and event times -- Some practical considerations for analysis of spotted microarray data -- Statistical applications using DNA microarrays for cancer diagnosis and prognosis -- Profiling high-dimensional protein expression using MALDI-TOF: mass spectrometry for biomarker discovery -- Statistical approaches for high dimensional data derived from high throughput assays: a case study of protein expression levels in lung cancer -- Spatial modeling of multilocus data -- Software for genomic data -- Bayesian sensitivity analyses of confounded treatment effects -- Interpreting longitudinal studies of QOL with nonignorable dropout -- Estimation of cumulative incidence in the presence of competing risks -- Pitfalls in the design, conduct and analysis of randomized clinical trials -- Dose-intensity analysis -- Sequential randomization.
標題 ： Cancer - Research - Statistical methods. -
標題 ： Clinical trials - Statistical methods. -
標題 ： Research Design. -
標題 ： Clinical Trials. -
標題 ： Data Interpretation, Statistical. -
版本 ： 2nd ed.
ISBN ： 0824723392
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245 00$aHandbook of statistics in clinical oncology /$c[edited by] John Crowley, Donna Pauler Ankerst.
250 $a2nd ed.
260 $aBoca Raton :$c2006.$bChapman & Hall/CRC,
300 $a617 p. :$bill. ;$c25 cm.
504 $aIncludes bibliographical references and index.
505 0 $aOverview of phase I trials -- Phase I and phase I/II dose finding algorithms using continual reassessment method -- Choosing a phase I design -- Pharmacokinetics in clinical oncology: statistical issues -- Practical implementation of the continual reassessment method -- Overview of Phase II clinical trials -- Designs based on toxicity and response -- Phase II trials using time-to-event endpoints -- Phase II selection designs -- On use of covariates in randomization and analysis of clinical trials -- Factorial designs with time to event endpoints -- Noninferiority trials -- Power and sample size for phase III clinical trials of survival -- Early stopping of cancer clinical trials -- Design and analysis of quality of life data -- Economic analyses alongside cancer clinical trials -- Prognostic factor studies -- Statistical methods to identify predictive factors -- Explained variation in proportional hazards regression -- Constructing prognostic groups by tree-based partitioning and peeling methods -- Clinical monitoring based on joint models for longitudinal biomarkers and event times -- Some practical considerations for analysis of spotted microarray data -- Statistical applications using DNA microarrays for cancer diagnosis and prognosis -- Profiling high-dimensional protein expression using MALDI-TOF: mass spectrometry for biomarker discovery -- Statistical approaches for high dimensional data derived from high throughput assays: a case study of protein expression levels in lung cancer -- Spatial modeling of multilocus data -- Software for genomic data -- Bayesian sensitivity analyses of confounded treatment effects -- Interpreting longitudinal studies of QOL with nonignorable dropout -- Estimation of cumulative incidence in the presence of competing risks -- Pitfalls in the design, conduct and analysis of randomized clinical trials -- Dose-intensity analysis -- Sequential randomization.
650 $aCancer$xResearch$xStatistical methods.$324189
650 $aClinical trials$xStatistical methods.$324190
650 $aNeoplasms$xtherapy.$324191
650 $aResearch Design.$324192
650 $aClinical Trials.$324193
650 $aComputational Biology.$324194
650 $aData Interpretation, Statistical.$324195
700 $aCrowley, John,$d1946-$324196
700 $aAnkerst, Donna Pauler.$324197
856 41$2http$uhttp://www.statsnetbase.com/books/4152/dk3170_chfm.pdf$zHandbook of statistics in clinical oncology (full text) (STATSnetBASE)
Handbook of statistics in clinical oncology /[edited by] John Crowley, Donna Pauler Ankerst. - 2nd ed. - Boca Raton :Chapman & Hall/CRC,2006. - 617 p. :ill. ;25 cm.
Includes bibliographical references and index.
Overview of phase I trials -- Phase I and phase I/II dose finding algorithms using continual reassessment method -- Choosing a phase I design -- Pharmacokinetics in clinical oncology: statistical issues -- Practical implementation of the continual reassessment method -- Overview of Phase II clinical trials -- Designs based on toxicity and response -- Phase II trials using time-to-event endpoints -- Phase II selection designs -- On use of covariates in randomization and analysis of clinical trials -- Factorial designs with time to event endpoints -- Noninferiority trials -- Power and sample size for phase III clinical trials of survival -- Early stopping of cancer clinical trials -- Design and analysis of quality of life data -- Economic analyses alongside cancer clinical trials -- Prognostic factor studies -- Statistical methods to identify predictive factors -- Explained variation in proportional hazards regression -- Constructing prognostic groups by tree-based partitioning and peeling methods -- Clinical monitoring based on joint models for longitudinal biomarkers and event times -- Some practical considerations for analysis of spotted microarray data -- Statistical applications using DNA microarrays for cancer diagnosis and prognosis -- Profiling high-dimensional protein expression using MALDI-TOF: mass spectrometry for biomarker discovery -- Statistical approaches for high dimensional data derived from high throughput assays: a case study of protein expression levels in lung cancer -- Spatial modeling of multilocus data -- Software for genomic data -- Bayesian sensitivity analyses of confounded treatment effects -- Interpreting longitudinal studies of QOL with nonignorable dropout -- Estimation of cumulative incidence in the presence of competing risks -- Pitfalls in the design, conduct and analysis of randomized clinical trials -- Dose-intensity analysis -- Sequential randomization.
ISBN: 0824723392
Standard No.: 9780824723392
LCCN: 2006273842Subjects--Topical Terms:
24189
Cancer
--Research
LC Class. No.: RC267 / .H36 2006
Dewey Class. No.: 616.99/400727
National Library of Medicine Call No.: 2006 B-354
Includes bibliographical references and index.
Overview of phase I trials -- Phase I and phase I/II dose finding algorithms using continual reassessment method -- Choosing a phase I design -- Pharmacokinetics in clinical oncology: statistical issues -- Practical implementation of the continual reassessment method -- Overview of Phase II clinical trials -- Designs based on toxicity and response -- Phase II trials using time-to-event endpoints -- Phase II selection designs -- On use of covariates in randomization and analysis of clinical trials -- Factorial designs with time to event endpoints -- Noninferiority trials -- Power and sample size for phase III clinical trials of survival -- Early stopping of cancer clinical trials -- Design and analysis of quality of life data -- Economic analyses alongside cancer clinical trials -- Prognostic factor studies -- Statistical methods to identify predictive factors -- Explained variation in proportional hazards regression -- Constructing prognostic groups by tree-based partitioning and peeling methods -- Clinical monitoring based on joint models for longitudinal biomarkers and event times -- Some practical considerations for analysis of spotted microarray data -- Statistical applications using DNA microarrays for cancer diagnosis and prognosis -- Profiling high-dimensional protein expression using MALDI-TOF: mass spectrometry for biomarker discovery -- Statistical approaches for high dimensional data derived from high throughput assays: a case study of protein expression levels in lung cancer -- Spatial modeling of multilocus data -- Software for genomic data -- Bayesian sensitivity analyses of confounded treatment effects -- Interpreting longitudinal studies of QOL with nonignorable dropout -- Estimation of cumulative incidence in the presence of competing risks -- Pitfalls in the design, conduct and analysis of randomized clinical trials -- Dose-intensity analysis -- Sequential randomization.
ISBN: 0824723392
Standard No.: 9780824723392
LCCN: 2006273842Subjects--Topical Terms:
24189
Cancer
--Research
LC Class. No.: RC267 / .H36 2006
Dewey Class. No.: 616.99/400727
National Library of Medicine Call No.: 2006 B-354
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